Indian journal of Research in Homeopathy is a medical journal aimed at improving the understanding and research in Homeopathy by publishing quality articles . It publishes articles on homeopathic researches that advances or illuminates homeopathic science , educate the journal readers & promotes debate.

Tuesday, July 27, 2010

A case of vitiligo treated by sulphur -D.K.Jha, L.Debata Regional Research Institute ( Homeopathy), Puri, Orissa

vitiligo before treatment


vitiligo during treatment

A case of vitiligo treated by sulphur
D.K.Jha, L.Debata
Regional Research Institute ( Homeopathy), Puri, Orissa

Vitiligo , as a cosmetic problem , is a source of great embrrassment to dark skinned people. An attempt was made by the CCRH to ascertain the role of homeopathy therapy and to identify homeopathic medicines useful in the management of vitiligo. Here is a case from the ongoing clinical research study on vitiligo at Regional Reasearch Institute(Homeopathy), Puri, treated by Sulphur. The case was followed up over a period of 2 years with marked improvement in white patches which is evident from photographs.

Key words: homeopathy, vitiligo, sulphur


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Thursday, July 22, 2010

Prevalence of Thyroid Disorders in School Children In Delhi - Post lodization Scenario An epidemiological survey conducted under the first phase of EMR project on "Effects of Homoeopathic treatment on natural history of autoimmune thyroiditis"

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Prevalence of Thyroid Disorders in School Children In Delhi - Post lodization Scenario
An epidemiological survey conducted under the first phase of EMR project on "Effects of
Homoeopathic treatment on natural history of autoimmune thyroiditis"
V.K. Chauhan1
, R.K. Manchanda 2
, Archan a Narang1
* , R.K. Marwaha 3
, Saurav Arora1
, Latika Nagpal
1
1. Dr. B. R. Sur Homoeopathic Medical College & Hospital, New Delhi,
2. Directorate of ISM&H, Delhi,
3. Institute of Nuclear Medicine & Allied Sciences, Timarpur, Delhi 

This article was published in Indian Journal of Research in Homoeopathy
Vol. 3, No. 3, July-September 2009

Screening of 4543 children between 6-18 years of age from different schools of Delhi was done
during the first phase of research study under EMR project by AYUSH, for thyroid function
status-clinically, serologically & ultrasonographically. Data of 4506 children has been analyzed
& it has been found that goiter is prevalent at mild endemic level in children (17%) even after
two decades of iodization. Significant increase in anti TPO ab positivity (6.39%) and thyroid
dysfunction (11.92%) raises suspicion about the role of environmental goitrogens and prolonged
iodine supplementation.
Key words: anti thyro-peroxidase antibody (anti TPO ab), free T3 (FT3), free T4 (FT4), goiter, Iodine
deficiency disorders (IDDs), subclinical hypothyroidism, thyroid autoimmunity, universal salt iodization
(USI).

Link : http://www.box.net/shared/v1nlgs8gvn

Wednesday, July 7, 2010

Lycopodine from Lycopodium clavatum extract inhibits proliferation of HeLa cells through induction of apoptosis via caspase-3 activation – a potential & promising use in chemotherapy

Lycopodine from Lycopodium clavatum extract inhibits proliferation of HeLa cells through induction of apoptosis via caspase-3 activation.

Mandal SK, Biswas R, Bhattacharyya SS, Paul S, Dutta S, Pathak S, Khuda-Bukhsh AR.

Cytogenetics and Molecular Biology Laboratory, Department of Zoology, University of Kalyani, Kalyani-741235, West Bengal, India.

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Abstract

Crude ethanolic extract of the plant Lycopodium clavatum has long been used in complementary and alternative medicine for treating various liver ailments and Alzheimer's disease. It has also been claimed to have potential anti-cancer properties in vivo in mice chronically fed liver carcinogens, p-dimethylamino azobenzene (initiator) and phenobarbital (promoter). Incidentally, crude ethanolic extract of Lycopodium clavatum is a mixture of some 201 alkaloids. In order to ascertain if any major fraction can be attributed to have pronounced anti-cancer effect, we examined this major fraction by eluting the crude extract in petroleum ether:ethyl aetate (17:3 vol/vol;) solvent and tried to understand its underlying mechanism. Studies on morphological changes, cell viability and cytotoxicity by microscopy and FACS, Western blot and immunofluorescence of Bcl-2, Bax, cytochrome c, caspase-3 were conducted. Lycopodine was found to induce chromatin condensation, inter-nucleosomal DNA fragmentation and enhanced cell population in sub-G1 region along with increase in reactive oxygen species generation and mitochondrial membrane potential depolarization, release of cytochrome c and activation of caspase-3 which are the events closely involved in apoptosis. An overall analysis of results showed that Lycopodine considerably inhibited growth of HeLa cells which indicates its potential use in chemotherapy.

Source : Pubmed